MICU Education

University of Pittsburgh

Antibiotics and Drug Interactions

Sepsis is one of the most common diagnosis in ICU. Thus, it is important to learn about antibiotics commonly used. Also, as most patients have complex medical history and are usually on many medications, care needs to be taken about drug interactions.


To learn about antibiotics and associated drug interactions, refer to the following presentation:

  Drug Interactions - antibiotics    

Additional Reading

For further reading, refer to section on antimicrobial therapy (section D) in the recent Surviving sepsis campaign guidelines published in 2012.

For review of recent literature, visit PulmCCM.


Dellinger RP et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med. 2013 Feb;39(2):165-228. doi: 10.1007/s00134-012-2769-8. Epub 2013 Jan 30.